About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3689380
Allelic
Composition
Cftrtm2Mrc/Cftrtm2Mrc
Genetic
Background
B6.129S6-Cftrtm2Mrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cftrtm2Mrc mutation (0 available); any Cftr mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• abnormal nasal potential difference (J:112450)
• abnormal nasal potential difference (J:112450)
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes (J:112450)
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes (J:112450)

growth/size/body
• reduced at 21 days of age relative to wild-type mice, but not at 7 or 14 days of age (J:112450)
• reduced at 21 days of age relative to wild-type mice, but not at 7 or 14 days of age (J:112450)

digestive/alimentary system
N
• able to eat a solid diet without developing intestinal blockage (J:112450)
• able to eat a solid diet without developing intestinal blockage (J:112450)

immune system
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes (J:112450)
• increased inflammatory response to chronic Pseudomonas aeruginosa infection, identical to that in Cftrtm1Unc homozygotes (J:112450)

Mouse Models of Human Disease
OMIM ID Ref(s)
Cystic Fibrosis; CF 219700 J:112450


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory