Phenotypes for Slc16a2 MGI:3688510 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Slc16a2^tm1.1Sref/Y
Genetic Background	involves: 129/Sv * 129P2/OlaHsd

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc16a2^tm1.1Sref mutation (1 available); any Slc16a2 mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal circulating hormone level ( J:113732 )

• serum levels of rT3 (reverse T3, competitive inhibitor of T3) are lower than wild-type littermates

decreased circulating thyroxine level ( J:113732 )

• T4 serum levels are lower than male wild-type littermates

increased triiodothyronine level ( J:113732 )

• mutants have higher serum T3 levels than male wild-type littermates

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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