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Phenotypes Associated with This Genotype
Genotype
MGI:3687637
Allelic
Composition
Mmp2tm1Ito/Mmp2tm1Ito
Recktm1Ito/Recktm1Ito
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp2tm1Ito mutation (1 available); any Mmp2 mutation (25 available)
Recktm1Ito mutation (1 available); any Reck mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 2/3 die by E11 and none survive beyond E11.5, however exhibit partial rescue of the phenotypes seen in single Reck homozygotes such as increased body size and tissue integrity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory