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Phenotypes Associated with This Genotype
Genotype
MGI:3664253
Allelic
Composition		 Npr1tm1(Npr1)Unc/Npr1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr1tm1(Npr1)Unc mutation (1 available); any Npr1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased systemic arterial blood pressure ( J:46175 )
• males exhibit blood pressures an average of 5.2 mmHg below controls
• similar to wild-type, dietary salt does not affect blood pressure

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory