Phenotypes Associated with This Genotype

Genotype
MGI:3641450

• Allelic Composition: Tg(CD2-Sh2d1a)#Vei/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased natural killer cell mediated cytotoxicity ( J:110195 )

• overexpression considerably enhances the capacity to kill CD48+ C4.4-25 target cells in vitro; a moderate increase in the killing of other CD48+ targets is also observed

hematopoietic system

increased natural killer cell mediated cytotoxicity ( J:110195 )

• overexpression considerably enhances the capacity to kill CD48+ C4.4-25 target cells in vitro; a moderate increase in the killing of other CD48+ targets is also observed