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Phenotypes Associated with This Genotype
Genotype
MGI:3629752
Allelic
Composition
Artm2(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Artm2(AR)Dmr mutation (1 available); any Ar mutation (22 available)
Tg(TRAMP)8247Ng mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice

endocrine/exocrine glands
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice

reproductive system
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory