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Phenotypes Associated with This Genotype
Genotype
MGI:3624553
Allelic
Composition
Mecp2tm1Hzo/Y
Genetic
Background
129S7/SvEvBrd-Mecp2tm1Hzo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm1Hzo mutation (1 available); any Mecp2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• 100% of males display tremors
• performance on a thin horizontal wooden dowel is impaired in older (35-36 weeks of age) but not younger (8-9 weeks of age) males
• in the wire suspension test, young males (8-9 weeks of age drop earlier than wild-type
• 100% of males display stereotypic forepaw movements (rapid and repetitive movement of the forelimbs, often bring them together)

Mouse Models of Human Disease
OMIM ID Ref(s)
Rett Syndrome; RTT 312750 J:78009


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory