Mouse Genome Informatics
hm
    Ctnna2tm1Mta/Ctnna2tm1Mta
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• most homozygotes die with 24 hours after birth

nervous system
• null mutants show some subtle disorders in laminar formation in the hippocampus
• Purkinje cell migration in the cerebellum is partially blocked in null mice
• dendrites of cultured hippocampal neurons from null mutants differ in their fine morphology compared to wild-type neurons; many dendritic spines are elongated in mutant neurons, with variable length of the dendritic spines

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:83635