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Phenotypes Associated with This Genotype
Genotype
MGI:3623448
Allelic
Composition
Ifngtm1Ts/Ifngtm1Ts
Genetic
Background
NOD.Cg-Ifngtm1Ts Prkdcscid
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifngtm1Ts mutation (18 available); any Ifng mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• when diabetic NOD splenocytes are transferred into mutant NOD.scid mice only 23% of recipients become diabetic (determined by monitoring urine glucose level) 7 weeks after transfer, but 100% of wild-type NOD.Scid mice are diabetic within 5 weeks

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
J:72818


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory