Mouse Genome Informatics
ht
    Engtm1Hma/Eng+
129P2/OlaHsd-Engtm1Hma
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
cardiovascular system
• occasional mice exhibit extensive dilated and weak-walled vessels
• elastin support fibers surrounding fragile vessels are disorganized and sparsely distributed
• smooth muscle cells surrounding the fragile vessels are disorganized and sparsely distributed

muscle
• smooth muscle cells surrounding the fragile vessels are disorganized and sparsely distributed

Mouse Models of Human Disease
OMIM IDRef(s)
Telangiectasia, Hereditary Hemorrhagic, of Rendu, Osler, and Weber; 187300 J:73415