Phenotypes for Apc Egfr MGI:3623317 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Apc^Min/Apc⁺ Egfr^Wa5/Egfr⁺
Genetic Background	involves: BALB/cAnN * C3H/HeN * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^Min mutation (12 available); any Apc mutation (151 available)
Egfr^Wa5 mutation (2 available); any Egfr mutation (88 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased tumor incidence ( J:92308 )

• 46% reduction in the number of macroscopic intestinal polyps in comparison to mice heterozygous only for Apc^Min at 3 months of age

• no reduction in tumor size

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24