Phenotypes Associated with This Genotype

Genotype
MGI:3622997

• Allelic Composition: Neurog1^tm1And/Neurog1^tm1And; Neurog2^tm2Fgu/Neurog2^tm2Fgu
• Genetic Background: involves: 129/Sv * C57BL/6J * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neuron differentiation ( J:59428 )

• neuronal patterning is abnomal in the thalamus, indicating misspecification of neurons; a population of ventral neurons in the dorsal tetncephalon are of dorsal origin

abnormal thalamus morphology ( J:59428 )

• the dorsal thalamus of double mutants is abnormal with an enlargement of the ventricular zone and a reduction in the size of the mantle zone

• neuronal patterning is abnomal in the thalamus, indicating misspecification of neurons

• at E12.5, there is an increase in the number of cells expressing a pan-neuronal marker compared to wild-type

cellular

abnormal neuron differentiation ( J:59428 )

• neuronal patterning is abnomal in the thalamus, indicating misspecification of neurons; a population of ventral neurons in the dorsal tetncephalon are of dorsal origin