Phenotypes Associated with This Genotype

Genotype
MGI:3622100

• Allelic Composition: Spag16^tm2Jfs/Spag16^tm2Jfs
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

teratozoospermia ( J:107006 )

♂ • disorganization of the sperm axonemal structure is observed

♂ • only a small number of null sperm are motile and showed progressive forward motility; the mean curvilinear velocity of mutant sperm is significantly lower in mutants compared to homozygotes

asthenozoospermia ( J:107006 )

♂ • motility of sperm in mutants is defective

reproductive system

teratozoospermia ( J:107006 )

♂ • disorganization of the sperm axonemal structure is observed

♂ • only a small number of null sperm are motile and showed progressive forward motility; the mean curvilinear velocity of mutant sperm is significantly lower in mutants compared to homozygotes

asthenozoospermia ( J:107006 )

♂ • motility of sperm in mutants is defective

small testis ( J:107006 )

♂ • a general trend toward smaller testes in mutants is observed

male infertility ( J:107006 )

♂ • homozygous males are infertile because no pregnancies are produce in 2 months of mating

endocrine/exocrine glands

small testis ( J:107006 )

♂ • a general trend toward smaller testes in mutants is observed