Mouse Genome Informatics
ht
    Lmnatm1Stw/Lmna+
involves: 129S1/Sv * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
homeostasis/metabolism
• on a high fat diet, females develop mild insulin resistance that correlates with increased body weight, no insulin resistance is seen in males
• on a normal diet, serum glucose, insulin, and triglyceride levels are normal, insulin sensitivity and glucose tolerance
• on a high fat diet, females develop increased insulin but not glucose levels

adipose tissue
N
• no signs of lipoatrophy are seen (J:75101)

liver/biliary system
N
• liver morphology is normal (J:75101)

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Lipodystrophy, Familial Partial, Type 2; FPLD2 151660 J:75101