Phenotypes Associated with This Genotype

Genotype
MGI:3620909

• Allelic Composition: Zmpste24^tm1Sgy/Zmpste24⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal thoracic vertebrae morphology ( J:79501 )

• at 15 months of age in 2 of 2 heterozygotes degraded transverse and spinous processes are seen

abnormal lumbar vertebrae morphology ( J:79501 )

• at 15 months of age in 2 of 2 heterozygotes degraded transverse and spinous processes are seen

growth/size/body

weight loss ( J:79501 )

• seen in older heterozygotes (around 15 months of age)

behavior/neurological

weakness ( J:79501 )

• appear weak at 15 months of age

integument

alopecia ( J:79501 )

• at 15 months of age