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Phenotypes Associated with This Genotype
Genotype
MGI:3619350
Allelic
Composition
Pigatm1Tak/Pigatm1Tak
Tg(Zp3-cre)1Gwh/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pigatm1Tak mutation (1 available); any Piga mutation (4 available)
Tg(Zp3-cre)1Gwh mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• eggs are severely deficient in their ability to fuse with sperm
• multiple sperm can enter perivitelline space without initiating a block to polyspermy
• sperm-egg fusion is blocked

cellular


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory