Phenotypes for Lep Mapk8 MGI:3619044 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Lep^ob/Lep^ob Mapk8^tm1Wag/Mapk8^tm1Wag
Genetic Background	B6.Cg-Lep^ob Mapk8^tm1Wag

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lep^ob mutation (5 available); any Lep mutation (19 available)
Mapk8^tm1Wag mutation (1 available); any Mapk8 mutation (71 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:80452 )

• decreased weight gain relative to Lep^ob single homozygotes

homeostasis/metabolism

decreased circulating glucose level ( J:80452 )

• decreased blood glucose level relative to Lep^ob single homozygotes

decreased circulating insulin level ( J:80452 )

• decreased blood insulin level relative to Lep^ob single homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23