Mouse Genome Informatics
cx
    Prkdcscid/Prkdcscid
Tg(TcraAI4)1Dvs/0
Tg(TcrbAI4)1Dvs/0

NOD.Cg-Prkdcscid Tg(TcraAI4)1Dvs Tg(TcrbAI4)1Dvs
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hematopoietic system
• mice exhibit a complete absence of CD4 T cells expressing the transgenes but transgene-expressing CD8 T cells are present

immune system
• mice exhibit a complete absence of CD4 T cells expressing the transgenes but transgene-expressing CD8 T cells are present
• female NOD.scid transgenic mice display accerlerated diabetes development compared to standard NOD females

Mouse Models of Human Disease
OMIM IDRef(s)
Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:93553