Phenotypes Associated with This Genotype

Genotype
MGI:3618328

• Allelic Composition: Ssb^tm1Rjma/Ssb^tm1Rjma
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:105552 )

• no homozygotes detected from E6.0 onward

• possible that death occurs before implantation

embryo

inner cell mass degeneration ( J:105552 )

• inner cell mass begins to degenerate starting after E3.0

abnormal trophoblast giant cell morphology ( J:105552 )

• trophoblast more persistent than inner cell mass but cell nuclei smaller than controls