Mouse Genome Informatics
hm
    Hgdaku/Hgdaku
either: (involves: 129/Sv * BALB/cByJ * NB) or (involves: 129/Sv * C57BL/6J * NB)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
homeostasis/metabolism
• high levels of homogenistic acid
• urine gradually turns dark over several days
• causes darkening of bedding
• ochronosis which is typical of alkaptonuria in humans does not occur in mice

skeleton
N
• arthritis which is typical of alkaptonuria in humans does not occur in mice (J:16506)

renal/urinary system
• high levels of homogenistic acid
• urine gradually turns dark over several days
• causes darkening of bedding
• ochronosis which is typical of alkaptonuria in humans does not occur in mice

Mouse Models of Human Disease
OMIM IDRef(s)
Alkaptonuria 203500 J:16506