About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3608972
Allelic
Composition		 Vangl2Lp/Vangl2+
MkksGt(OST367255)Lex/Mkks+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J * LPT/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MkksGt(OST367255)Lex mutation (0 available); any Mkks mutation (27 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:102697 )
• all double heterozygotes die by E13.5

hearing/vestibular/ear
abnormal outer hair cell stereociliary bundle morphology ( J:102697 )
• some outer hair cell stereociliary hair bundles have a flattened shape
abnormal orientation of outer hair cell stereociliary bundles ( J:102697 )
• some outer hair cell stereociliary hair bundles are misoriented

nervous system
abnormal outer hair cell stereociliary bundle morphology ( J:102697 )
• some outer hair cell stereociliary hair bundles have a flattened shape
abnormal orientation of outer hair cell stereociliary bundles ( J:102697 )
• some outer hair cell stereociliary hair bundles are misoriented

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory