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Phenotypes Associated with This Genotype
Genotype
MGI:3606456
Allelic
Composition		 Prss12tm1Dgen/Prss12tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prss12tm1Dgen mutation (1 available); any Prss12 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased thigmotaxis ( J:101679 )
• exhibit a significant decrease in the time spent in the central region during open field testing, indicating a possible increase in anxiety
decreased locomotor activity ( J:101679 )
• exhibit a significant decrease in total distance traveled during open field testing

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory