Mouse Genome Informatics
either: 129S6/SvEvTac-Cpt1atm1Pwo or (involves: 129S6/SvEvTac * C57BL/6NTac)
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
• after a 24 hour fast serum glucose levels are significantly decreased compared to wild-type mice
• after a 24 hour fast serum free fatty acid levels are significantly increased compared to wild-type mice

other phenotype
• when heterozygotes are crossed to heterozygotes more than the expected percentage of heterozygous pups are found, greater than 80% compared to the expected 67%
• however, when heterozygotes are crossed to wild-type mice no significant deviation from the expected ratio of heterozygous to wild-type offspring is seen

Mouse Models of Human Disease
Carnitine Palmitoyltransferase I Deficiency 255120 J:101934