Mouse Genome Informatics
cn
    Fmr1tm1Cidz/Fmr1tm1Cidz
Tg(Pcp2-cre)2Mpin/0

involves: 129S1/Sv * 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• the percentage, amplitude, and velocity of conditioned responses were reduced in the 3rd and 4th training sessions; however the startle response was normal (J:101021)

nervous system
• the length of Purkinje cell spine heads and necks is increased (J:101021)
• induction of long term depression in Purkinje cells is significantly enhanced when stimulating parallel fibers (J:101021)

Mouse Models of Human Disease
OMIM IDRef(s)
Fragile X Mental Retardation Syndrome 300624 J:101021