Analysis Tools
digestive/alimentary system
|
• at 10 weeks, these mutants develop only ~14% of the polyp number detected in the intestinal tracts of mice heterozygous for Apctm1Mmt alone
• the size of intestinal polyps is significantly smaller (<1.0 mm) than that observed in mice heterozygous for Apctm1Mmt alone, with no polyps larger than 2.0 mm in diameter
• histologically, well-developed polyps are not covered with the normal intestinal epithelium and appear flatter than polyps found in Apctm1Mmt heterozygous controls
• notably, no colonic polyps are observed
|
