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Phenotypes Associated with This Genotype
Genotype
MGI:3603339
Allelic
Composition
Kittm1Bpr/Kit+
Genetic
Background
either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kittm1Bpr mutation (0 available); any Kit mutation (139 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• interstitial cells of Cajal (ICC) hyperplasia in the cecum and large bowel that is much less extensive than in homozygotes
• develop small cecal gastrointestinal stromal tumors (GIST)

neoplasm
• develop small cecal gastrointestinal stromal tumors (GIST)

pigmentation
N
• normal coat color unlike homozygotes that have a white coat

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
gastrointestinal stromal tumor DOID:9253 OMIM:606764
J:100778


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/11/2017
MGI 6.08
The Jackson Laboratory