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Phenotypes Associated with This Genotype
Genotype
MGI:3590085
Allelic
Composition
Fem1btm1Jfma/Fem1btm1Jfma
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fem1btm1Jfma mutation (0 available); any Fem1b mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• defective glucose-induced and arginine-induced acute-phase insulin secretion
• display a hyperglycemic response to the intraperitoneal glucose tolerance test

endocrine/exocrine glands
• pancreatic insulin content is increased in fasted mice
• defective glucose-induced and arginine-induced acute-phase insulin secretion

Mouse Models of Human Disease
OMIM ID Ref(s)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM 125853 J:100017


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory