About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3587786
Allelic
Composition
Ndst1tm1Ekf/Ndst1tm1Ekf
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndst1tm1Ekf mutation (0 available); any Ndst1 mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Newborn Ndst1tm1Ekf/Ndst1tm1Ekf mice display lung atelectasia

mortality/aging
• pups cyanotic and died neonatally (J:63996)
• pups cyanotic and died neonatally (J:63996)
• some death between E14.5 and E18.5 (J:63996)
• some death between E14.5 and E18.5 (J:63996)

respiratory system
• less secreted surfactant protein but produced by more cells (J:63996)
• less secreted surfactant protein but produced by more cells (J:63996)
• lungs fail to inflate at birth (J:63996)
• lungs fail to inflate at birth (J:63996)

homeostasis/metabolism

Mouse Models of Human Disease
OMIM ID Ref(s)
Respiratory Distress Syndrome in Premature Infants 267450 J:63996


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory