Phenotypes Associated with This Genotype

Genotype
MGI:3587763

• Allelic Composition: Myo7a^816SB/Myo7a^816SB
• Genetic Background: involves: BALB/cRl * 47BS/Rl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal cochlear hair cell stereociliary bundle morphology ( J:46373 )

• disorganized formation of stereocilia rows

• some hair cells with several small clumps of stereocilia

abnormal orientation of cochlear hair cell stereociliary bundles ( J:46373 )

• orientation of rows of cochlear hair cell stereocilia erratic

absent cochlear microphonics ( J:46373 )

• no cochlear microphonics responses

abnormal auditory summating potential ( J:46373 )

• no summating potential responses

nervous system

abnormal cochlear hair cell stereociliary bundle morphology ( J:46373 )

• disorganized formation of stereocilia rows

• some hair cells with several small clumps of stereocilia

abnormal orientation of cochlear hair cell stereociliary bundles ( J:46373 )

• orientation of rows of cochlear hair cell stereocilia erratic

absent cochlear microphonics ( J:46373 )

• no cochlear microphonics responses

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Usher syndrome type 1		DOID:0110826	OMIM:276900	J:46373