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Phenotypes Associated with This Genotype
Genotype
MGI:3586835
Allelic
Composition
Htttm1Hay/Htttm1Hay
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm1Hay mutation (0 available); any Htt mutation (73 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most die at around E7.5 and E8.5 and all are dead at E9.5
• most die at around E7.5 and E8.5 and all are dead at E9.5

embryo
• gastrulation is disturbed
• E8.5 embryos fail to neurulate, which leads to disorganization of embryos
• embryos are small and underdeveloped at E7.5
• extraembryonic membranes are fragmented at E7.5 and a connection between the allanotis and the placenta does not form

growth/size/body
• embryos are small and underdeveloped at E7.5

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Huntington Disease; HD 143100 J:25941


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory