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Phenotypes Associated with This Genotype
Genotype
MGI:3586835
Allelic
Composition
Htttm1Hay/Htttm1Hay
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm1Hay mutation (0 available); any Htt mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most die at around E7.5 and E8.5 and all are dead at E9.5 (J:25941)
• most die at around E7.5 and E8.5 and all are dead at E9.5 (J:25941)
• most die at around E7.5 and E8.5 and all are dead at E9.5 (J:25941)
• most die at around E7.5 and E8.5 and all are dead at E9.5 (J:25941)

embryogenesis
• gastrulation is disturbed (J:25941)
• gastrulation is disturbed (J:25941)
• embryos are small and underdeveloped at E7.5 (J:25941)
• embryos are small and underdeveloped at E7.5 (J:25941)
• extraembryonic membranes are fragmented at E7.5 and a connection between the allanotis and the placenta does not form (J:25941)
• extraembryonic membranes are fragmented at E7.5 and a connection between the allanotis and the placenta does not form (J:25941)
• E8.5 embryos fail to neurulate, which leads to disorganization of embryos (J:25941)
• E8.5 embryos fail to neurulate, which leads to disorganization of embryos (J:25941)

growth/size/body
• embryos are small and underdeveloped at E7.5 (J:25941)
• embryos are small and underdeveloped at E7.5 (J:25941)

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Huntington Disease; HD 143100 J:25941


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory