Mouse Genome Informatics
tg
    Tg(Amelx)42Msnd/Tg(Amelx)42Msnd
involves: C57BL/6J * CBA/J * DBA/2J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
craniofacial
• transmission electron microscopy of the enamel matrix of neonatal incisors reveals non-uniformity in the size of the self-assembled amelogenin nanospheres and disruption of the normally evenly-spaced, parallel arrangement of the hydroxyapatite crystallites
• scanning electron micrographs of incisors of 6 week old mice reveal loss of the normal boundary definiton of the rods comprising the enamel and abnormal porosity of the structure formed by the rods

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Amelogenesis Imperfecta, Type IE; AI1E 301200 J:100004