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Phenotypes Associated with This Genotype
Genotype
MGI:3584136
Allelic
Composition
Tg(TcraTcrbNY8.3)1Pesa/?
Genetic
Background
involves: C57BL/6 * NOD * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(TcraTcrbNY8.3)1Pesa mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• insulitis at 3 weeks less than in controls
• insulitis at 6 weeks of age significantly greater than in controls

homeostasis/metabolism
• diabetes develops in 26% (males) to 33% (females) of mice
• diabetes slow to develop and moderate

endocrine/exocrine glands
• insulitis at 3 weeks less than in controls
• insulitis at 6 weeks of age significantly greater than in controls

Mouse Models of Human Disease
OMIM ID Ref(s)
Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:44202


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory