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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• following energy stress (induced by treatment with 2-deoxyglucose) mutant MEFs display a less pronounced decrease in cell size compared to wild-type cells; however under normal conditions no differences in cell size or proliferation are seen
• following ATP depletion mutant MEFs are resistant to dephosphorylation of RPS6K and EIF4EBP1
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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