Phenotypes Associated with This Genotype

Genotype
MGI:3583444

• Allelic Composition: Vezf1^tm1Stmn/Vezf1^tm1Stmn
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:99326 )

• stillborn pups detected at approximately 60% of the expected Mendelian frequency

cardiovascular system

abnormal blood vessel morphology ( J:99326 )

• between E12.5 and birth, embryos display varying degrees of vascular malformation in the head and trunk region

hemorrhage ( J:99326 )

• stillborn pups display intraembryonic hemorrhage

• Background Sensitivity: between E12.5 and birth, embryos display varying degrees of vascular malformation in the head and trunk region

embryo

embryo phenotype ( J:99326 )

N • embryos appear phenotypically normal up to E11.5

N • between E12.5 and birth many embryos were resorbed