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Phenotypes Associated with This Genotype
Genotype
MGI:3583131
Allelic
Composition
Itgb2tm1Bay/Itgb2tm1Bay
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb2tm1Bay mutation (1 available); any Itgb2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• myeloid hyperplasia in bone marrow
• myeloid hyperplasia of splenic red pulp

hematopoietic system
• myeloid hyperplasia in bone marrow
• myeloid hyperplasia of splenic red pulp

integument
N
• Background Sensitivity: did not develop progressive dermatitis in the C57BL/6J background

Mouse Models of Human Disease
OMIM ID Ref(s)
Leukocyte Adhesion Deficiency, Type I; LAD 116920 J:13599


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory