About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3581822
Allelic
Composition
Tg(GFAP)10Mes/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• severely affected mice die around 14 days of age; less affected mice live for more than 1 year
• mice display <10% mortality at about 30 days of age

growth/size/body
• mice show significantly decreased body weights at 6 weeks and three months relative to wild-type

nervous system
• astrocytes are enlarged and contain large eosinophilic aggregations resembling Rosenthal fibers;

Mouse Models of Human Disease
OMIM ID Ref(s)
Alexander Disease; ALXDRD 203450 J:99256


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory