Phenotypes for Hras Syngap1 MGI:3581305 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hras^tm1Grnt/Hras^tm1Grnt Syngap1^tm1Grnt/Syngap1⁺
Genetic Background	involves: 129P2/OlaHsd * MF1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hras^tm1Grnt mutation (0 available); any Hras mutation (30 available)
Syngap1^tm1Grnt mutation (0 available); any Syngap1 mutation (49 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

reduced long-term potentiation ( J:98903 )

• long term potentiation induced by 150 pulses of 5 Hz stimulation in the hippocampal CA1 region was reduced compared to wildtype and single homozygous Hras1 mutants

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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