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Phenotypes Associated with This Genotype
Genotype
MGI:3580088
Allelic
Composition
Arhgap6/Hccs/Mid1tm1Hzo/Y
Tg(EIIa-cre)C5379Lmgd/?
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgap6/Hccs/Mid1tm1Hzo mutation (0 available); any Hccs mutation (4 available)
Tg(EIIa-cre)C5379Lmgd mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no hemizygous mice born
• 15 of 21 embryos abnormal at E9.5 and E10.5
• mosaic animals were present and were healthy and fertile

embryo
• many embryos undergoing resorption by E9.5-E10.5
• gastrulation defects

growth/size/body

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
microphthalmia DOID:10629 J:80528


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory