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Phenotypes Associated with This Genotype
Genotype
MGI:3579767
Allelic
Composition		 Col4a1deltaex40/Col4a1deltaex40
Genetic
Background		 B6.129S-Col4a1deltaex40
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col4a1deltaex40 mutation (0 available); any Col4a1 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:98572 )
• homozygous embryos not viable after mid-embryogenesis

embryo
abnormal parietal endoderm morphology ( J:98572 )
• procollagen accumulation in parietal endoderm cells
abnormal Reichert's membrane morphology ( J:98572 )
• embryonic Reichert's membrane lacked Col4a1 in basement membrane

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory