Phenotypes Associated with This Genotype

Genotype
MGI:3577358

• Allelic Composition: Mmp3^tm1Mrl/Mmp3^tm1Mrl
• Genetic Background: either: (129S7/SvEvBrd X B10.RIII)N2 or ((involves: 129S7/SvEvBrd * C57BL/6) X B10.RIII)N2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

joint inflammation ( J:46038 )

• presence of inflammatory cells in joints

autoimmune arthritis ( J:46038 )

• incidence and severity of collagen induced arthritis greater than controls at day 16, equivalent to level induced in B10.RII mice

osteoarthritis ( J:46038 )

• erosion of articular cartilage

immune system

joint inflammation ( J:46038 )

• presence of inflammatory cells in joints

autoimmune arthritis ( J:46038 )

• incidence and severity of collagen induced arthritis greater than controls at day 16, equivalent to level induced in B10.RII mice

osteoarthritis ( J:46038 )

• erosion of articular cartilage