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Phenotypes Associated with This Genotype
Genotype
MGI:3574962
Allelic
Composition		 Mthfrtm1Rzn/Mthfr+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mthfrtm1Rzn mutation (2 available); any Mthfr mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal lipid homeostasis ( J:67779 )
• lipid accumulation in the aorta near the aortic valve but no foam cells
• some microvesicular steatosis in the liver

liver/biliary system
microvesicular hepatic steatosis ( J:67779 )
• some microvesicular steatosis in the liver

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory