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Phenotypes Associated with This Genotype
Genotype
MGI:3574279
Allelic
Composition
Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic
Background
FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cecr2Gt(pGT1)1Hemc mutation (0 available); any Cecr2 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• exencephaly penetrance was 0% unlike in other genetic backgrounds
• increased cranial neural tube width
• at the 16 somite stage the neural tube is closed in only about half the embryos
• penetrance is 1.6% at greater than N10

hearing/vestibular/ear
N
• no cochlear defects are detected

embryo
• increased cranial neural tube width
• at the 16 somite stage the neural tube is closed in only about half the embryos

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT anencephaly DOID:0060668 OMIM:206500
J:96325


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory