Mouse Genome Informatics
ht
    Phox2a/Inppl1tm1Ssch/Phox2a+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
growth/size
• injection of insulin caused more profound hypoglycemia in heterozygotes than in wild-type mice

homeostasis/metabolism
• injection of D-glucose resulted in a more rapid glucose clearance in heterozygous compared to wild-type
• in response to insulin stimulation GLUT4 glucose transporter and glycogen synthesis are increased more profoundly in skeletal muscle of heterozygotes compared to wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM 125853 J:96443