Mouse Genome Informatics
ht
    Notch3tm1Ul/Notch3+
Not Specified
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• vascular smooth muscle is normal in the thoracic aorta and common carotid arteries and electron microscopic examination detected no abnormalities in the thoracic and abdominal aortas or the carotid, leptomeningeal, and cerebral cortical penetrating arteries

normal phenotype
• heterozygotes are viable with normal growth, reproduction, behavior, and morphology of the brain, heart, lung, eye, and skin

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL 125310 J:95927