Mouse Genome Informatics
hm
    Notch3tm1Ul/Notch3tm1Ul
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
cardiovascular system
N
• vascular smooth muscle is normal in the thoracic aorta and common carotid arteries and light and electron microscopic examination detected no abnormalities in the thoracic and abdominal aortas or the carotid, leptomeningeal, and cerebral cortical penetrating arteries (J:95927)

normal phenotype
• homozygotes are viable with normal growth, reproduction, and morphology of the brain, heart, lung, eye, and skin

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Cerebral Arteriopathy, Autosomal Dominant, with Subcortical Infarcts and Leukoencephalopathy; CADASIL 125310 J:95927