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Phenotypes Associated with This Genotype
Genotype
MGI:3526582
Allelic
Composition
Homer2tm1Mhd/Homer2tm1Mhd
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Homer2tm1Mhd mutation (1 available); any Homer2 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• carbachol stimulated acinar cells showed a higher increase in intracellular calcium concentration due to increased calcium release from internal stores than controls
• two-fold increased frequency of intracellular calcium oscillations in acinar cells in response to stimulation with bombesin or CCK compared to controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory