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Phenotypes Associated with This Genotype
Genotype
MGI:3522660
Allelic
Composition
Foxm1tm1Rhc/Foxm1tm1Rhc
Genetic
Background
involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxm1tm1Rhc mutation (0 available); any Foxm1 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system

neoplasm
• after diethylnitrosamine (DEN) and phenobarbitol (PB) treatment, multiple hepatic adenomas were observed in liver sections from these mice at 23, 33 and 50 weeks of age

homeostasis/metabolism
• after diethylnitrosamine (DEN) and phenobarbitol (PB) treatment, multiple hepatic adenomas were observed in liver sections from these mice at 23, 33 and 50 weeks of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hepatocellular carcinoma DOID:684 OMIM:114550
J:89472


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/05/2019
MGI 6.13
The Jackson Laboratory