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Phenotypes Associated with This Genotype
Genotype
MGI:3522571
Allelic
Composition
Myh9tm1Maco/Myh9tm1Maco
Genetic
Background
involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh9tm1Maco mutation (1 available); any Myh9 mutation (218 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no viable homozygous embryos are found after E7.5 (J:94940)
• die at E6.5 (J:163702)

embryo
• the organization of the cell layers is disrupted (J:94940)
• lack identifiable cell layers at E6.5 (J:163702)
• the visceral endoderm is disarrayed and the cells retain a cuboidal shape (J:94940)
• disorganized at E6.5 (J:163702)
• cell-cell borders lack cadherin 1 (J:163702)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory