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Phenotypes Associated with This Genotype
Genotype
MGI:3514177
Allelic
Composition		 Abcg8tm1Elk/Abcg8+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcg8tm1Elk mutation (1 available); any Abcg8 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:94759 )
• plasma cholesterol level was decreased by 26%

liver/biliary system
abnormal hepatobiliary system physiology ( J:94759 )
• under conditions that force biliary sterol secretion, cholesterol secretion into bile was reduced relative to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory