Phenotypes Associated with This Genotype

Genotype
MGI:3513052

• Allelic Composition: Disp1^icb/Disp1^icb
• Genetic Background: involves: 129/Sv * C57BL/6J * SWR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:94270 )

• homozygotes die before E9.5

cardiovascular system

abnormal vascular development ( J:94270 )

abnormal heart development ( J:94270 )

craniofacial

abnormal facial morphology ( J:94270 )

• gross defects in facial development are seen

embryo

abnormal somite development ( J:94270 )

limbs/digits/tail

abnormal limb morphology ( J:94270 )

• gross defects in limb development are seen

nervous system

abnormal brain development ( J:94270 )

• defects in neural development are seen

growth/size/body

abnormal facial morphology ( J:94270 )

• gross defects in facial development are seen